How to Impose Microscopic Reversibility in Complex Reaction Mechanisms
نویسندگان
چکیده
منابع مشابه
How to impose microscopic reversibility in complex reaction mechanisms.
Most, but not all, ion channels appear to obey the law of microscopic reversibility (or detailed balance). During the fitting of reaction mechanisms it is therefore often required that cycles in the mechanism should obey microscopic reversibility at all times. In complex reaction mechanisms, especially those that contain cubic arrangements of states, it may not be obvious how to achieve this. T...
متن کاملAnalyzing mechanisms and microscopic reversibility of self-assembly.
We use computer simulations to investigate self-assembly in a system of model chaperonin proteins, and in an Ising lattice gas. We discuss the mechanisms responsible for rapid and efficient assembly in these systems, and we use measurements of dynamical activity and assembly progress to compare their propensities for kinetic trapping. We use the analytic solution of a simple minimal model to il...
متن کاملThe Principle of Microscopic Reversibility.
In recent years increasing use has been made of a new postulate which perhaps cannot yet be stated in its final form, but which requires in a general way in the case of a system in thermodynamic equilibrium not only that the total number of molecules leaving a given state in unit time shall on the average equal the number arriving in that state in unit time, but also that the number leaving by ...
متن کاملOn thermodynamic and microscopic reversibility
The word ‘reversible’ has two (apparently) distinct applications in statistical thermodynamics. A thermodynamically reversible process indicates an experimental protocol for which the entropy change is zero, whereas the principle of microscopic reversibility asserts that the probability of any trajectory of a system through phase space equals that of the time reversed trajectory. However, these...
متن کاملReversibility of a phosphoroclastic reaction.
Reaction 1 occurring with reaction 2 involves carbon dioxide fixation. Koepsell & Johnson (1942) obtained a cell-free extract from Clo8tridium butylicum which converts pyruvic acid into acetic acid, carbon dioxide and hydrogen, and requires phosphate for the reaction. Later Koepsell, Johnson & Meek (1944) found that inorganic phosphate is taken up and labile phosphate appears. The overall react...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2004
ISSN: 0006-3495
DOI: 10.1529/biophysj.103.038679